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Combining MSC-Exos with radical-trapping antioxidants or iron chelators could produce synergistic therapies, harnessing rapid radical scavenging alongside prolonged microenvironment modulation

As we age, natural GHK levels in the body decline, from around 200 ng/mL in the plasma of a 20-year-old to roughly 60 ng/mL by age 60

435 Sirolimus has also shown efficacy in rare diseases such as lymphangioleiomyomatosis (NCT00414648) and renal angiomyolipoma in tuberous sclerosis complex (TSC) (NCT00457808), 436,437 where mTOR-driven cell proliferation and dysregulated autophagy are key features