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Back Secher, A, Jelsing, J, Baquero, et al (2014) 'The arcuate nucleus mediates GLP- 1RA liraglutide- dependent weight loss', Journal Clinical Investigation , 124, 447388

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[] Moreover, GLP-1 inhibits the secretion of glucagon from alpha cells of pancreatic islets and as an extra-pancreatic effect, it directly shows the inhibitory responses on appetite centers and delays the gastric emptying time, which may lead to felling satiety

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Patients experiencing severe nausea, vomiting, abdominal distension, or known gastroparesis before surgery may require individualized anesthesia planning, delayed procedures, modified fasting instructions, or additional airway precautions to reduce aspiration risk