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While some patients report reduced alcohol interest during semaglutide therapy, the medication is not approved or proven effective for treating alcohol use disorder

In vivo studies with long-acting glucagon analogue suggest that hypoaminoacidaemia could be an important contributing mechanism to the observed increase in energy expenditure with glucagon agonism, but it also leads to enhanced lean mass loss [63]

Yin W, Xu S, Wang Z, Liu H, Peng L, Fang Q et al (2018) Recombinant human GLP-1(rhGLP-1) alleviating renal tubulointestitial injury in diabetic STZ-induced rats