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Analyses were carried out using R Statistical Software (version 4.1.1, Foundation for Statistical Computing) and TSA software (Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigs Hospitalet) [22]

doi: 10.1007/s00428-019-02533-9 37 CohenJNJosephNMNorthJPOnoderaCZembowiczALeBoitPE