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Nonetheless, our peripheral GSH findings suggests that intracellular GSH may be more sensitive to early stages of disease and that extracellular changes become apparent in more severe stages of cognitive impairment such as AD

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Untill this is researched and understood fully we literally are going round in circles

Oxidative stress, inflamm-aging and immunosenescence

A significant downregulation of CRAT was further confirmed in another 122-paired OC tissues and corresponding adjacent non-tumor tissues by immunohistochemistry (IHC) analysis (Fig