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By targeting these receptors, the drugs blunt dopamine release and reduce reward signaling

In addition to other signals, the presence of fiber, protein, or healthy fats triggers its release from cells in the small intestine and colon

22 Animal studies have shown GLP-1 agonists reduce consumption of alcohol, cocaine, amphetamine, and nicotine in rodents

At most concentrations, 50 units falls within the established therapeutic range and is not dangerous when prescribed appropriately and escalated gradually