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24 Numerous studies have shown that the dysregulation of TGF-1/Smad represents an important pathogenic pathway in various tissue fibrogenesis, including lung, liver and kidney fibrosis

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Again, the supervillin, a 205 kDa actin-binding protein, structurally homologue to gelsolin and villin, together with its muscle specific isoform, archvillin, interact and transactivate AR [50, 51]

The gut and the brain are in constant biochemical conversation through the vagus nerve, the immune system, the enteric nervous system, the bacterial metabolites that cross into circulation, and the inflammatory cytokines released when intestinal barriers fail

Busso D, David A, Penailillo R, Echeverra G, Rigotti A, Kovalskys I, Gmez G, Corts Sanabria LY, Ypez Garca MC, Pareja RG et al (2021) Intake of vitamin E and C in women of reproductive age: results from the Latin American study of nutrition and health