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Some of the most frequent include changes in cost or insurance coverage, unpleasant side effects like nausea, constipation, vomiting or fatigue and the achievement of a targeted weight or health goal

Physiology & Behavior , 122, 201207

have not been reviewed by the FDA for safety, effectiveness, or quality

In one trial, those switched to placebo injections not only began to reaccumulate body fat, but their waist circumference also began to revert back to its original size