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M.et al (2015)

Every individual has a certain capacity to process and eliminate histaminethis is their "bucket." Histamine enters the bucket from multiple sources: it is produced endogenously by mast cells and basophils, synthesized by certain bacteria in the gut microbiome, and ingested directly through histamine-rich or histamine-liberating foods (such as aged cheeses, fermented foods, and certain fruits)

352(a) and (bb)]

The functional relationships between the intestine and the pancreatic islet were named by Unger and Eisentraut in 1969 [30] as the enteroinsular axis, while the criteria formulated by Creutzfeldt [31] considered a molecule to be incretin when it is secreted in response to nutrients, and that physiological concentrations increased the secretion of insulin in the presence of high glucose concentrations

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