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Also, the significance of this peptide's therapeutic benefit against amplified and advanced paracetamol toxicity remains to be further postulated, particularly considering the extensive investigation of gastrointestinal peptides in gastrointestinal and liver physiology (38), physiological mediators in NSAIDs-induced impairment of gastric mucosal defense and adaptation (39), and brain-gut peptide regulation (40)

Research has confirmed that AOD-9604 produces significant fat metabolism effects without binding to growth hormone receptors or affecting carbohydrate metabolism

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systemic = whole-body tissue effects)