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Doesnt matter, because that doesnt change whether Im giving you a statin, you know, and so, and so if it doesnt change how Im going to treat you, it doesnt matter

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Various agents such as anaphylatoxins, antigens, bradykinin, cytokines/lymphokines, hormones, immunoglobulin E (IgE), neurotransmitters, neuropeptides, viruses, bacterial toxins, medications, and stress can activate macrophages (Tsai et al., 2010)