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Meanwhile, we treated HepG2 cells with different concentrations of hDPP4 and found that the levels of IKK, p-P65 S536 /P65 ratio, and p-IKB S36 /IKB ratio were significantly enhanced to different degrees, but the activation of IKK-NFB signaling pathway induced by hDPP4 was remarkably inactivated by sitagliptin (Fig

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The lawsuit centers on allegations that the drug makers failed to adequately warn patients about serious gastrointestinal side effects, including gastroparesis, intestinal obstructions, and pancreatitis