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In healthy individuals, GLP-1 is released after food consumption, particularly in response to proteins and fats, signaling satiety and stimulating insulin secretion

For eligible and willing patients, bariatric surgery, which provides sustained benefits, may be the best option from a clinical and economic perspective

" Ask your healthcare provider for a referral to a registered dietitian and exercise physiologist to get professional support for your health journey using GLP-1 medications," Nasser says

Fasting blood glucose and insulin resistance improves within 6 days of gastric bypass and occurs before any weight loss (34)

First, we saw Semaglutide (Ozempic/Wegovy) , a single-hormone agonist that offered ~15% weight loss