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Similarly, Sarrou et al

It contains naltrexone (an opioid antagonist) and bupropion (an atypical antidepressant) that work on different neurochemical pathwaysprimarily the hypothalamus and reward centersrather than on GLP-1 receptors

But it has primarily been the latter that has driven the ongoing epidemic crisis in the United States

Decreases in binge eating behaviors This 2024 review also found that GLP-1 medications may help reduce binge eating by lowering appetite and food cravings

Some patients reach a higher dose for stronger results, while others may stay at a moderate level if they are losing weight consistently and feeling well