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Why Individual Results Vary and What That Means for Treatment Patients differ in metabolism, hormone signaling, stress patterns, sleep quality, comorbidities, and eating behaviors

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Use in Special Populations Patients with Renal Insufficiency Because most of DPP-4 inhibitors are eliminated renally, it is expected that their pharmacokinetic profile will be influenced by impairments in renal function and that their plasma levels will increase in proportion to renal failure [44]

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