International Counterfeit cancer drugs, antibiotics, paracetamol, and more were seized in Pakistan and India
These can indicate degradation even if the vial appears unchanged
The subjective/interoceptive effects of alcohol significantly contribute to craving, consumption, and relapse, and thus represent an important therapeutic target (Grant and Bennett 2003
This stepwise escalation principle mirrors the approach used for licensed medicines such as semaglutide (Wegovy, UK SmPC available via the electronic Medicines Compendium) and tirzepatide (Mounjaro, UK SmPC available via the electronic Medicines Compendium), both of which are approved by the MHRA and recommended within relevant NICE guidance for specific indications
Assuming rebates of 50% across all GLP-1 products in 2024 would mean net spending of around $14 billion in 2024