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3m), and the ATP levels declined during regeneration and were improved in SLC25A51-overexpressing livers (Fig

Estrogen plays a direct anabolic role in muscle protein synthesis, and its decline accelerates the onset of sarcopenia, the age-related loss of muscle mass that predicts falls, metabolic disease, and reduced healthspan

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19 , e46666 (2018)

Although alterations in genetic factors have been linked with its etiology, exponential accumulation of environmental entities such as reactive oxygen species (ROS) initiate a cyclic chain reaction resulting in accumulation of cellular inclusions, dysfunctional mitochondria, and overwhelming of antioxidant machinery, thus accelerating disease pathogenesis