When histamine levels exceed the body's degradative capacity, individuals may experience a wide range of symptoms including headaches, flushing, nasal congestion, gastrointestinal disturbances (such as bloating, diarrhoea, or abdominal pain), skin reactions (urticaria, itching), palpitations, dizziness, and fatigue
While the rate of degradation can vary, significant potency loss can occur in as little as 48-72 hours at room temperature
You are allowed to go slowly
Brouilette, S., Singh, R
If you have certain digestive disorders, including pernicious anemia, or have had gastric bypass surgery, oral B12 will simply not work because you can't absorb it correctly