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These medications work by mimicking the bodys natural hormone GLP-1, which helps regulate appetite, blood sugar, and digestion

Nevertheless, whether the inhibitory effect of SCFAs on HDACs is dependent on expression of FFAR2 and FFAR3 is controversial, because SCFAs seem to enter cells directly through membrane transport proteins on the cell surface (85)

Furthermore, lixisenatide was associated with a reduced risk of new-onset macroalbuminuria when adjusted for baseline HbA1c [hazard ratio, 0.81 (95% confidence interval 0.660.99

Both medications share a similar side effect profile because both activate the GLP-1 receptor

Here is a comparison of the starting approaches