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Biotin-enhanced formulas Some ALA supplements include added biotin as a precaution, based on limited evidence primarily from animal studies suggesting high doses of ALA might interfere with biotin metabolism.57 While the real-world significance in humans remains unclear, manufacturers include biotin to help prevent any potential deficiency

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58 Consequently, GLP-1 RAs are currently evidence-based treatments for common conditions that not only differentially affect persons with SMI-SUD but also contribute to the morbidity and mortality of these conditions