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Zepbound (tirzepatide) is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that is FDA-approved along with increased physical activity and a reduced-calorie diet for chronic weight management in adults with a starting body mass index (BMI) of: 30 kg/m^2 or higher (obesity) or 27 kg/m^2 or higher (overweight) with at least one weight-related condition such as high cholesterol, high blood pressure (hypertension), type 2 diabetes, heart disease, or obstructive sleep apnea

In contrast to the majority of anti-diabetic compounds, DPP-4 inhibitors do not produce weight gain as a side effect, which is crucial for limiting body weight gain during long-term therapy for diabetes

Starting your day with protein helps support muscle repair and makes it easier to hit your daily protein needs, which is especially important when youre eating less overall

The exception is the two advanced doses 12.5 and 15 mg/week which are $649/month

Phase 3 clinical trials are urgently needed to clarify the efficacy and safety of this new approach for treatment of obesity and type 2 diabetes