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In approximately 80% of patients, elevated levels of glycine can be detected in the CSF, while CSF levels of PLP are decreased in 81% of cases and urinary vanilloid acid is elevated in 91% of patients [37]

High levels of ROS, excessive inflammatory cells and cytokines in the wound microenvironment, insufficient new blood vessels, and weakened cell proliferation are the key factors that lead to the difficult healing of diabetic wounds 24

Graphical Abstract Similar content being viewed by others Background Idiopathic intracranial hypertension (IIH) is a debilitating condition characterized by raised intracranial pressure causing chronic headaches and papilledema with the risk of permanent visual loss, which most commonly occurs in young obese women [1]

Alternatively to MPT in the control of OMM permeabilization, Bcl-2 family members are also known to play a major function

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