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There are several underlying reasons for the methyl trap: the concentration of Hcy drops, oxidative stress inhibits MS, and the drop in [SAM] releases the inhibition of MTHFR, which drives more folate towards the 5mTHF form

To view a copy of this licence, visit About this article Cite this article Baker, P.R., Li, A.S., Griffin, B.R

[DOI] [PMC free article] [PubMed] [Google Scholar] 183.Schmidt P.H.S., Pasqualotto E., Dos Santos H.V., de Souza L.S.N., Dos Santos B.E., Chavez M.P., Ferreira R.O.M., Hohl A., Ronsoni M.F., van de Sande-Lee S