[DOI] [PMC free article] [PubMed] [Google Scholar] 184.Kupst M.J., Butt Z., Stoney C.M., Griffith J.W., Salsman J.M., Folkman S., Cella D
Injection technique and site selection Clinical trials administered retatrutide via subcutaneous injection, the same route used for semaglutide and tirzepatide
Foundayo is used along with a reduced-calorie diet and increased physical activity to reduce and maintain weight in adults with obesity or with overweight plus a weight-related condition
Privacy and interoperability burden: Medication and weight data are sensitive
Areas Requiring Further Investigation Further research is needed to clarify long-range receptor signaling behavior, tissue-specific pathway effects, molecular signaling durability, model-to-human translation, and how findings vary across study designs