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A 2019 review in the Journal of Physiology noted that "IGF-1 signalling and mechanical loading converge on mTORC1 to regulate skeletal muscle protein synthesis, and the relative contribution of each remains an active area of investigation" [6]

A perfect patient for non-surgical fat removal should be in generally good health and have a localized fat area that does not respond to diet and exercise

That includes biosimilar adoption, low value drug exclusions, patient and copay assistance programs, and active management of high-cost categories like GLP1s

It is not approved for human consumption, therapeutic use, or veterinary use