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Rather, it promotes the development of broadly inhibitory antibodies, the researchers report

Reporting summary Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article

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Unsurprisingly, this led to increased coverage for Wegovy, and the coverage landscape is likely to change again with the expected approval in this indication for key competitor Zepbound

What Happens at Steady State: Plateau Dynamics and Extended Dosing One of the most clinically significant findings from the 12mg retatrutide dosage cohort was the absence of a weight loss plateau at 48 weeks