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Metformin, a first-line biguanide medication, reduces glucose production and improves insulin sensitivity, whilst semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), enhances insulin secretion and promotes significant weight loss

GLP-1 constipation can occur when the normal bowel function is disrupted, leading to infrequent and difficult-to-pass stools

iron must be in a divalent (Fe 2+ ) state or combine with a transporter protein to be absorbed by intestinal epithelial cells

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With a gin and a whisky on the way too, we caught up with Frank Grillo again to discover the latest from the brand