incretin hormone glp-1 Incretin-based therapy of metabolic disease GLP-1 Genetics: How Genes Affect

The fat bomb exploded but no one heard the bang

Key points The incretin hormone glucagon-like peptide 1 (GLP1) promotes satiety and potentiates insulin release and suppression of glucagon release in response to the ingestion of nutrients

NICE guidance (TA875) supports the use of semaglutide 2.4 mg (Wegovy) for adults with a BMI of 35 kg/m or above alongside at least one weight-related condition, within a specialist weight management service (with lower BMI thresholds applicable for certain ethnic groups and other commissioning criteria)

Who should not combine keto and GLP-1 Not everyone should attempt this combination

At the same time, the median primary care visit is just 15.7 minutes, and most clinics do not offer weight care support, like nutritional counseling or support groups, to increase the chances of long-term success