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Cell Mol Life Sci 77:17451770 Lv S, Sylvestre M, Prossnitz AN, Yang LF, Pun SH (2021) Design of polymeric carriers for intracellular peptide delivery in oncology applications

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In studies using human gingival and periodontal stem cells [4, 45], Epitalon enhanced the expression of: Nestin (neural progenitor marker) GAP43 (axon growth) -Tubulin III and Doublecortin (neuronal differentiation and migration) Together, these shifts suggest Epitalon may prime stem cells toward neuronal lineage, hinting at applications in regenerative neurology or brain injury recovery models

Its most prominent function has been suggested to regulate apoptosis in senescent cells