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These findings highlight the potential of A4 as a lead compound for developing multifunctional anti-Alzheimer drugs and highlight the importance of further structural optimization to enhance its therapeutic effects (545)

Petraglia F, Vannuccini S, Santulli P, Marcellin L, Chapron C

DEM exposure resulted in a clear accumulation of Keap1-GFP in cytoplasmic autophagosomal foci, an accumulation of Nrf2-GFP in the nucleus and an accumulation of Srxn1-GFP in the cytoplasm, which is in agreement with the current qualitative understanding of the Nrf2 pathway

Vitamine B3 draagt bij tot een normale psychologische functie en de normale werking van zenuwen en het zenuwstelsel