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separation was carried out using a non-isocratic method, starting at 23% ACN and climbing to 31 % ACN over 9 minutes, at ambient temperature and a flow rate of 0.3 mL/min

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The typical dose is 1 to 2 puffs from an HFA inhaler 15 to 30 minutes before exercise

In patients with Type 2 diabetes, GLP-1 concentrations are decreased in response to an oral glucose load

Most protocols use morning dosing, partly because of the cognitive enhancement intent (effects during waking hours) and partly because some users report mild stimulant-like effects that interfere with sleep if dosed too late