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Systematic review registration: 1 Introduction Cancer is currently one of the main social, economic, and publichealth challenges ( Latin America and the Caribbean (LAC) is a region comprising 49 countries and territories (the term territories groups overseas and unincorporated areas) and can be subdivided into three subregions based on geographic location: Central America (8 countries), South America (12 countries and 1 territory), and the Caribbean (13 countries and 15 territories)

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How tirzepatide and niacinamide work together The interaction between tirzepatide and niacinamide is not a direct biochemical synergy in the sense of one molecule enhancing the receptor affinity or signaling cascade of the other