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Copper plays a role in collagen synthesis, extracellular matrix regulation, angiogenesis-related signaling, and antioxidant defense mechanisms

Reference Tolhurst et al., Diabetes (2012) Reference Shah & Vella, Reviews in Endocrine and Metabolic Disorders (2014) When SCFA-producing microbes decline, GLP-1 signaling weakens and metabolism slows

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Extremophiles are a group of single-celled organisms that can thrive in extreme conditions and surprisingly maintain their genomes despite exacerbated deamination rates

Its long been said that to stoke your metabolic furnace or avoid starvation mode you should eat small, frequent meals throughout the day