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In a small study involving older individuals, two weeks of supplementation with a combination of N-acety-l-cysteine (NAC) and glycine raised red blood cell (RBC) glutathione levels more effectively than either amino acid alone (Guthikonda, et al American Geriatrics Society,Annual Scientific Meeting, 2006.)
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Start titration exactly as recommended, because how quickly you escalate matters as much as what you change on the plate: Begin 0.25 mg once weekly for weeks 14 Move to 0.5 mg weekly for weeks 58 Continue gradual increases to your maintenance dose Pair careful titration with targeted, testable adjustments to meals, movement, and simple OTC supports to reduce the risk of severe gas and other GI symptoms as you adapt
Lin WM, Luo S, Muzikansky A, Lobo AZ, Tanabe KK, Sober AJ et al
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