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Signs to watch for include persistent itching, rash, swelling, or hives that dont resolve within 24-48 hours
doi: 10.3390/ijms20215384
Co-delivery techniques can modulate the signaling pathways that facilitate tumor survival (e.g., PI3K/AKT and NF-B) by sensitizing tumor cells to chemotherapy, overcoming multidrug resistance (MDR) by blocking efflux pumps and disrupting redox homeostasis, or enabling the spatiotemporal delivery of therapeutic agents (e.g., administering a chemotherapy-sensitizing agent followed by a cytotoxic drug) 81,82
We found that GPX3 overexpression could significantly up-regulate the phosphorylation of ERK1/2 but had a weak effect on JNK1/2 and p38