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Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney

How much choline you need How much choline you need each day depends on your age and sex: Babies up to 6 months: 125 mg Infants 7-12 months: 150 mg Kids 1-3: 200 mg Kids 4-8: 250 mg Kids 9-13: 375 mg Teen boys 14-18: 550 mg Teen girls 14-18: 400 mg Men 19+: 550 mg Women 19+: 425 mg Pregnant teens and women: 450 mg Breastfeeding teens and women: 550 mg Foods With Choline Many foods are a great source of protein, particularly meat, dairy, and fish but this puts people on a plant-based diet at a higher risk for choline deficiency

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Berberine's glucose and lipid effects appear at 900 to 1,500 mg daily in divided doses, a range replicated across multiple meta-analyses (Liang et al., 2019, 28 trials, 2,313 patients)