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Importantly, these efficacy results were seen with very low rates of clinically significant hypoglycemia and a safety and tolerability profile consistent with the GLP-1 receptor agonist class. Study design For the phase 3 trial, Frias and colleagues analyzed data from 1,879 adults with type 2 diabetes inadequately controlled with metformin therapy of at least 1,500 mg daily (mean age, 57 years
Statements Author contributions CL, CM, TT, and RK conceived the review and led the project administration
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owns stock in Medtronic, Eli Lilly and Novo Nordisk, and received research funding from Novo Nordisk for another project during the writing of this Review