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MIAMI, Oct
(eClinicalMedicine, 2024) - found that 52 weeks of once-weekly semaglutide at 1.0 mg reduced hip bone mineral density by 2.6% and lumbar spine BMD by 2.1% compared to placebo in 64 adults with elevated fracture risk
Instead, they act as ATP-independent holdases that bind misfolded or partially unfolded proteins, preventing their aberrant aggregation and facilitating subsequent degradation
[DOI] [PubMed] [Google Scholar] Mann RJ, Al-Sabah S, Lpez de Maturana R, Sinfield JK, Donnelly D
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