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AlphaFold), design novel molecules, optimize formulation, and even plan clinical trials

they may also have direct effects in the brain (animal studies show neuroprotection and reduced amyloid/tau pathology)

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Sosne et al., Exp Eye Res , 2002), suppresses NF-kB-mediated cytokine release, and reduces myofibroblast trans-differentiation, which the authors interpret as an anti-scarring effect

The PIONEER 7 trial confirmed the pattern with flexibly dosed oral semaglutide, reporting a mean body weight reduction of 2.9 kg vs 0.8 kg for sitagliptin at 52 weeks