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Impaired Adult Neurogenesis Recent studies suggest that impaired adult hippocampal neurogenesis may be an early etiological factor in Alzheimers, affecting neuronal migration and network formation prior to the appearance of amyloid or tau pathology

Test days on which a rat failed to meet the FR10 criterion were excluded from primary analyses of %appropriate responding, but response rate data were retained to capture potential deficits in overall responding

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After undergoing this treatment regimen, hair regrowth was observed

Treatment studies administering folinic acid at doses typically ranging from 0.5 to 2 mg/kg/day reported improvements in communication, irritability, attention, stereotypy, and neurological signs