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In a study comparing an insulin-administered group and an oral antidiabetic agent-administered group among 382 newly diagnosed T2DM (average HbA1c 10.1%) over 2 weeks, the rate of reaching target blood glucose levels was higher when insulin was administered (insulin pump, MDI therapy, and oral antidiabetic agents: 97.1%, 95.2%, and 83.5%, respectively)

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Generally this weight is lost during the first 6 months of treatment

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Pharmacodynamics Fasting Plasma Glucose (FPG) levels were lowered under treatment with SAR425899