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The pharmacist planned to reduce all prandial doses equally to allow blood sugars to rise throughout the day and let the full effect of tirzepatide occur while limiting hypoglycemia due to insulin

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[PubMed ID: 17406579]

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3.2.2 BNIP3/NIX mediated mitophagy NIX, a protein with 50% homology to BNIP3 (Matsushima et al., 1998), binds to the mitochondrial outer membrane through its carboxyl transmembrane domain, thereby initiating mitophagy under ischemic or hypoxic conditions

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Vit-C-mediated restoration of TET was also described in four pre-clinical studies combining high dose VitC with chemotherapy [98], targeted therapy [22, 119] and ICI anti-PD-1 [90] (Figs

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