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Paradoxically, MMP, despite their degradative role, may also promote tumorigenesis by releasing sequestered growth factors and generating ROS via Rac1 signaling, thereby contributing to genomic instability (156)

Persistent very high levels (for example, sustained above 3 SDS in clinical context) may need clinician review, dose adjustment, or stopping

Schimidt HL, Garcia A, Martins A, Mello-Carpes PB, Carpes FP (2017) Green tea supplementation produces better neuroprotective effects than red and black tea in Alzheimer-like rat model

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