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Attention to the side effects of these drugs has focused on gastrointestinal symptoms, but bone health is an area where research is still early and conflicting

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The disease is often associated with serious complications, including cardiovascular disorders, kidney failure, and vision impairment, placing a substantial burden on patients and the healthcare system

A similar study was done on Sprague Dawley rats but with lower amounts of 0.0025, 0.01, 0.025, and 0.1 mg/kg/day