The predominant side effects include: Gastrointestinal symptoms : nausea, vomiting, diarrhoea, constipation, and abdominal pain (affecting 10-50% of patients depending on the specific product and dose, particularly during dose escalation) Injection site reactions : redness, itching, or discomfort at the subcutaneous injection site Hypoglycaemia : particularly when combined with insulin or sulphonylureas Decreased appetite : an intended therapeutic effect that contributes to weight loss However, some patients do report changes in urinary frequency or patterns
However, further research is needed to elucidate the specific roles of gut fungus-derived tyrosol and farnesol within the microbiotagutbrain axis
Livest Sci 152:200207 Long M, Yang S, Zhang W et al (2016) The influence of selenium yeast on hematological, biochemical and reproductive hormone level changes in Kunming mice following acute exposure to zearalenone
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