NAD+ serves as an essential coenzyme in the mitochondrial electron transport chain and as a critical substrate for sirtuins, PARPs, and CD38-type enzymes involved in DNA repair, stress resistance, and metabolic homeostasis
doi: 10.1038/nbt.3663 31 CoxMADuncanGSLinGHYSteinbergBEYuLXBrennerDet al
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Partially approved: Coverage may be approved with restrictions (quantity limits, specific dose requirements, etc.)
4.6 Metabolism Plasma, bile, urine, and fecal samples of intact SD rats or BDC rats after a single administration of [3H]BPC157 were analyzed by HPLC combined with a low-energy radionuclide detection technique to obtain the radiometabolite profiles of [3H]BPC157