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Treat that as a ceiling, not a forecast

This is not microdosing in the strict sense, but it applies the same principle of slower escalation

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Aggregate characterization often requires: Orthogonal analytical methods SEC coupled with MS Native mass spectrometry for biosimilars Stability-indicating analytical workflows Using multiple complementary techniques improves confidence in impurity detection and biosimilar comparability

doi: 10.3389/fimmu.2024.1393213 Received 04 March 2024 Accepted 24 May 2024 Published 13 June 2024 Volume 15 - 2024 Edited by Giovanni Mario Pes, University of Sassari, Italy Reviewed by Ariel Israel, Leumit Health Care Services, Israel Roberto Rosales-Reyes, National Autonomous University of Mexico, Mexico Updates Copyright 2024 Shah, Stone, Francis and Karafin