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But contact your prescribing provider if you experience severe vomiting or diarrhea lasting more than 24 hours, signs of significant dehydration (extreme dizziness, very dark urine, inability to keep fluids down), or if GI symptoms are severe enough to prevent adequate fluid intake for more than a day or two

Assessment and history A structured history should aim to distinguish (a) true vaginal mucosal symptoms, (b) vulvar dermatologic disease, (c) urinary tract symptoms, and (d) sexual function/arousal issues

What microdosing looks like Rather than starting at 2.5 mg, a microdosing approach might begin at 1.0 to 1.5 mg and increase in smaller increments: This approach requires compounded tirzepatide since brand-name pens do not allow sub-2.5 mg dosing