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Where many clinicians are landing these days in osteoarthritis care is this: helping patients understand that hurt does not equal harm, that pacing matters, and that exercises can be progressed over time

Br J Pharmacol 179(4):557570 Tuttle KR, Lakshmanan MC, Rayner B, Busch RS, Zimmermann AG, Woodward DB et al (2018a) Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial

As covered in an earlier analysis of CagriSemas Phase 3 data, the journey to that decision has not been without complexity