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Sangle P, Sandhu O, Aftab Z, Anthony AT, Khan S

In patients who already had substance use disorders, starting the GLP-1s was linked with a 31% lower risk of emergency department visits, 26% lower risk of hospitalizations, 25% lower risk of suicidal thoughts or attempts, 39% lower risk of overdose and 50% lower risk of death

The article points to people with severe renal impairment, a history of pancreatitis, or contraindications to either drug, saying they should work with a provider to explore other options

Second, your overall energy balance must favor loss of fat

Always use products from a reputable source and store them as directed